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First International IEEE EMBS Conference on Neural Engineering, 2003. Conference Proceedings.

DOI: 10.1109/cne.2003.1196888

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Reduced encoding of Diffusion Spectrum imaging with cross-term correction

Proceedings article published in 1970 by C. P. Lin, W. Y. I. Tseng ORCID, J. C. Weng, V. J. Wedeen, J. H. Chen
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Diffusion Spectrum MRI (DSI) has been demonstrated to be capable of defining orientations of intersecting fibers accurately. However, the scanning procedure is overly time-consuming under the current sampling scheme. We developed a reduced encoding scheme of DSI and proved that decreasing the acquisition points to 62% is feasible by diffusion cross-term correction. We calculated the diffusion cross-term from the acquired data in the center of q space by assuming that image corresponding to any diffusion encoding direction suffers b values from diffusion gradients, imaging gradients and the cross-term between diffusion gradients and imaging gradients. The data in outer q space was then corrected with diffusion cross-term and filled by the data acquired with opposite diffusion gradients according to the geometric symmetry of diffusion anisotropy. Both ex-vivo crossing capillaries phantom and ex-vivo rat brain models showed that this method can decrease DSI acquisition time while preserving the patterns and orientations of probability density function.