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American Society for Microbiology, Journal of Clinical Microbiology, 11(53), p. 3663-3666, 2015

DOI: 10.1128/jcm.01680-15

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Optimal Cutoff Titers for Indirect Immunofluorescence Assay for Diagnosis of Scrub Typhus

Journal article published in 2015 by Cherry Lim ORCID, Stuart D. Blacksell ORCID, Achara Laongnualpanich, Pacharee Kantipong, Nicholas Pj J. Day, Daniel H. Paris ORCID, Direk Limmathurotsakul
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT We determined the optimal cutoff titers in admission and convalescent-phase samples for scrub typhus indirect immunofluorescence assay using Bayesian latent class models. Cutoff titers of ≥1:3,200 in an admission sample or of a ≥4-fold rise to ≥1:3,200 in a convalescent-phase sample provided the highest accuracy (sensitivity, 81.6%; specificity, 100%).