We apply a density evaluation technique based on photometric redshifts, developed by our group, to estimate galaxy space density on the deep (z450~26) multi-wavelength GOODS-MUSIC catalogue. We find several groups and clusters in the redshift range 0.4-2.5. We present here an outline of the X-ray properties of our cluster sample as computed from the Chandra 2Ms data. A group at z = 0.96 could be associated to an extended X-ray source, while two clusters with masses of few times 1014Msolar have upper limits on their X-ray emission significantly lower than expected from their optical properties.