The study's purpose was to assess the effect of multiplanar reconstruction on precision of weight-bearing medial and lateral femoral cartilage (cMF, cLF) morphometry in maloriented coronal MR images. Twenty knees were scanned four times with a 1.0 Tesla extremity imager using a fat-suppressed T1-weighted three-dimensional spoiled gradient recalled echo sequence; twice with "best as" double bull's-eye orientation of the femoral condyles, and once each with 5° internal and external rotation. Multiplanar reconstruction was applied to maloriented scans to recover double bull's-eye orientation. Medial and lateral femoral cartilages were segmented and precision of bone area, cartilage volume and thickness (ThCtAB) evaluated for all scans. Test-retest precision (RMSCV%) of the double bull's-eye scans was 1.1% for total bone area and 4.1% for cartilage volume. Differences in precision between double bull's-eye and maloriented images were assessed. Higher precision errors were observed in malorientated images for all outcomes (1.7-4.8% for internally rotation scans; 1.7-4.8% for external rotation scans). Precision generally improved with multiplanar reconstruction correction (1.7-5.6% for internally rotated scans; 1.2-3.5% for external rotation scans). Precision of femoral cartilage morphometry is generally reduced when maloriented images are acquired. Multiplanar reconstruction can correct malorientated scans and recover precision losses. Measurements are affected in a rotationally and compartmentally dependent manner.