2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)
DOI: 10.1109/isbi.2014.6867976
Full text: Download
Connectivity analysis on diffusion MRI data of the whole-brain suffers from distortions caused by the standard echo-planar imaging acquisition strategies. These images show characteristic geometrical deformations and signal destruc-tion that are an important drawback limiting the success of tractography algorithms. Several retrospective correction techniques are readily available. In this work, we use a digital phantom designed for the evaluation of connectivity pipelines. We subject the phantom to a "theoretically correct" and plausible defor-mation that resembles the artifact under investigation. We correct data back, with three standard methodologies (namely fieldmap-based, reversed encoding-based, and registration-based). Finally, we rank the methods based on their geomet-rical accuracy, the dropout compensation, and their impact on the resulting connectivity matrices.