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Elsevier, Tetrahedron, 4(71), p. 648-653

DOI: 10.1016/j.tet.2014.12.024

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The effect of silica-coating on catalyst recyclability in ionic magnetic nanoparticle-supported Grubbs–Hoveyda catalysts for ring-closing metathesis

Journal article published in 2015 by Shu-Wei Chen, Zhi-Cheng Zhang, Ning Zhai, Chong-Min Zhong ORCID, Sang-Gi Lee
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The Grubbs–Hoveyda type ruthenium–carbene complexes have been covalently immobilized on both silica coated and uncoated magnetic nanoparticles utilizing an imidazolium salt linker. These MNP-supported catalysts showed comparable catalytic activity to the homogeneous imidazolium salt-tagged ruthenium catalyst in the ring-closing metathesis (RCM) of dienes, and could effectively catalyze RCM reactions in the presence of only 0.85 mol % Ru. The MNP-supported ruthenium catalysts could be easily recovered using an external magnet. The recyclability of the silica-coated MNP-supported catalysts was superior to silica uncoated MNP-supported catalysts allowing reuse 14 times, due to the increased compatibility of the silica-coated MNPs with the reaction medium.