Published in
American Society of Hematology, Blood, 2(122), p. 179-187, 2013
DOI: 10.1182/blood-2013-01-482224
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
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Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model
Journal article published in 2013 by
Patrick M. Younan,
Patricia Polacino,
John P. Kowalski,
Christopher W. Peterson,
Nicholas J. Maurice 
,
Nathaniel P. Williams,
On Ho,
Grant D. Trobridge,
Dorothee Von Laer,
Martin Prlic ,
Brian C. Beard,
Stephen DeRosa,
Shiu-Lok Hu,
Hans-Peter Kiem
,
Nathaniel P. Williams,
On Ho,
Grant D. Trobridge,
Dorothee Von Laer,
Martin Prlic ,
Brian C. Beard,
Stephen DeRosa,
Shiu-Lok Hu,
Hans-Peter Kiem
This paper is made freely available by the publisher.
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Abstract
Key Points Stem cell gene therapy results in enhanced virus-specific immunity and recovery of CD4+ T cells in a nonhuman primate model of AIDS. Gene therapy–mediated protection of stem cells results in a disease state similar to that observed in long-term nonprogressors.