Elsevier, Tetrahedron Letters, 9(54), p. 1129-1132
DOI: 10.1016/j.tetlet.2012.12.058
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Simple flow chemistry technology coupled to newly developed solid organosilica catalysts can be successfully applied to enhance the efficiency and selectivity of two representative homogeneous syntheses widely employed by chemical companies. The method is general and can be extended to many other reactions using similar solid catalysts to afford reactions that are faster and cleaner than conventional homogeneous and heterogeneous conversions.