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Cell Press, Cell Metabolism, 2(18), p. 153-161, 2013

DOI: 10.1016/j.cmet.2013.05.017

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Cellular Fatty Acid Metabolism and Cancer

Journal article published in 2013 by Erin Currie, Almut Schulze, Rudolf Zechner ORCID, Tobias C. Walther, Robert V. Farese
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Cancer cells commonly have characteristic changes in metabolism. Cellular proliferation, a common feature of all cancers, requires fatty acids for synthesis of membranes and signaling molecules. Here, we provide a view of cancer cell metabolism from a lipid perspective, and we summarize evidence that limiting fatty acid availability can control cancer cell proliferation.