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American Chemical Society, Journal of the American Chemical Society, 3(131), p. 890-891, 2009

DOI: 10.1021/ja807334b

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Boron Nitride Nanotubes Are Noncytotoxic and Can Be Functionalized for Interaction with Proteins and Cells

Journal article published in 2009 by Xing Chen, Peng Wu, Michael Rousseas, David Okawa, Zev Gartner, Alex Zettl ORCID, Carolyn R. Bertozzi
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We report the discovery that boron nitride nanotubes (BNNTs), isosteres of CNTs with unique physical properties, are inherently noncytotoxic. Furthermore, we developed a biomemetic coating strategy to interface BNNTs with proteins and cells. Finally, we showed that BNNTs can deliver DNA oligomers to the interior of cells with no apparent toxicity. This work suggests that BNNTs may be superior to CNTs for use as biological probes and in biomaterials.