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Public Library of Science, PLoS ONE, 7(7), p. e39860, 2012

DOI: 10.1371/journal.pone.0039860

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MassTRIX Reloaded: Combined Analysis and Visualization of Transcriptome and Metabolome Data

Journal article published in 2012 by Brigitte Wägele, Michael Witting ORCID, Philippe Schmitt-Kopplin, Karsten Suhre ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Systems Biology is a field in biological science that focuses on the combination of several or all “omics”-approaches in order to find out how genes, transcripts, proteins and metabolites act together in the network of life. Metabolomics as analog to genomics, transcriptomics and proteomics is more and more integrated into biological studies and often transcriptomic and metabolomic experiments are combined in one setup. At a first glance both data types seem to be completely different, but both produce information on biological entities, either transcripts or metabolites. Both types can be overlaid on metabolic pathways to obtain biological information on the studied system. For the joint analysis of both data types the MassTRIX webserver was updated. MassTRIX is freely available at www.masstrix.org.