Published in

Springer Nature [academic journals on nature.com], The ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2(3), p. 199-208, 2008

DOI: 10.1038/ismej.2008.93

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A comparison of homologous recombination rates in bacteria and archaea

Journal article published in 2008 by Michiel Vos, Xavier Didelot ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

It is a standard practice to test for the signature of homologous recombination in studies examining the genetic diversity of bacterial populations. Although it has emerged that homologous recombination rates can vary widely between species, comparing the results from different studies is made difficult by the diversity of estimation methods used. Here, Multi Locus Sequence Typing (MLST) datasets from a wide variety of bacteria and archaea are analyzed using the ClonalFrame method. This enables a direct comparison between species and allows for a first exploration of the question whether phylogeny or ecology is the primary determinant of homologous recombination rate.