Thieme Gruppe, Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, 2, p. 0247-0250, 2004
DOI: 10.1055/s-2003-44968
Wiley-VCH Verlag, ChemInform, 24(35), 2004
Full text: Unavailable
A flexible two-step asymmetric approach to N-protected (R)-5-alkyl tetramates and (R)-5-alkyl tetramic acid derivatives is described. The method is based on the diastereoselective alkylation of (R)-phenylglycinol derived tetramates 7 and 8, which are the first synthetic equivalents to chiral nonracemic tetramate 5-carbanionic synthons A.