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Psychiatry Online, The American Journal of Psychiatry, 4(168), p. 365-377

DOI: 10.1176/appi.ajp.2010.10070948

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Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder

Journal article published in 2011 by Geert J. Poelmans, David L. Pauls, Jan K. Buitelaar, Barbara Franke ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a highly heritable neuropsychiatric disorder. In the present study, the authors investigated the presence of genomic convergence in the top findings of the five published genome-wide association studies (GWASs) of ADHD. METHOD: The authors carried out bioinformatics pathway analyses, using the Ingenuity and BiNGO tools, as well as a systematic literature analysis of 85 genes from the five published GWASs containing single nucleotide polymorphisms associated with ADHD at a p value