Informed decision-making is the basis for the design of Net Zero Energy Buildings (NZEBs). This paper investigates the use of building performance simulation tools as a method of informing the design decision of NZEBs. The aim of this study was to develop a design decision making tool, ZEBO, for zero energy residential buildings in hot climates and to evaluate the effect of a simulation-based decision aid, on informed decision-making using sensitivity analysis. An assessment of the role of the BPS tools used in informing the decision-making was ascertained through cases studies, usability testing and several self-reported metrics. The paper provides results that shed light on the effectiveness of sensitivity analysis as an approach for informing the design decisions of NZEBs.