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Royal Society of Chemistry, Chemical Communications, 10(48), p. 1452-1454, 2012

DOI: 10.1039/c1cc14728e

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Modular synthesis of supramolecular ureidopyrimidinone-peptide conjugates using an oxime ligation strategy

Journal article published in 2012 by Re Roxanne Kieltyka, Roxanne E. Kieltyka, Mmc Maartje Bastings, Geert C. van Almen, Gc Geert van Almen, Pol Besenius ORCID, Ewl Erwin Kemps, Erwin W. L. Kemps, Pyw Patricia Dankers, Patricia Y. W. Dankers
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This paper is available in a repository.

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Abstract

A convenient method to prepare supramolecular bioconjugates in a facile and scalable manner is by a modular approach, whereby self-assembling units and peptides are coupled using oxime chemistry. We here report syntheses of bioactive ureidopyrimidinone-based peptide conjugates, and their resultant self-assembly into fibrous structures.