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Nature Research, Nature Biotechnology, 4(30), p. 365-365, 2012

DOI: 10.1038/nbt0412-365c

Nature Research, Nature Biotechnology, 9(28), p. 935-942, 2010

DOI: 10.1038/nbt.1666

Nature Research, Nature Biotechnology, 12(28), p. 1308-1308, 2010

DOI: 10.1038/nbt1210-1308c

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The BioPAX community standard for pathway data sharing

Journal article published in 2010 by Emek E. Demir, Michael P. Cary, Suzanne Paley, Ken Fukuda, Christian Lemer, Imre Vastrik, Guanming Wu, Peter D'Eustachio ORCID, Carl Schaefer, Joanne Luciano, Frank Schacherer, Irma Martinez-Flores, Zhenjun Hu, Veronica Jimenez-Jacinto, Geeta Joshi-Tope and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Biological Pathway Exchange (BioPAX) is a standard language to represent biological pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The rapid growth of the volume of pathway data has spurred the development of databases and computational tools to aid interpretation; however, use of these data is hampered by the current fragmentation of pathway information across many databases with incompatible formats. BioPAX, which was created through a community process, solves this problem by making pathway data substantially easier to collect, index, interpret and share. BioPAX can represent metabolic and signaling pathways, molecular and genetic interactions and gene regulation networks. Using BioPAX, millions of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases. This large amount of pathway data in a computable form will support visualization, analysis and biological discovery. © 2010 Nature America, Inc. All rights reserved. ; 0 ; SCOPUS: re.j ; info:eu-repo/semantics/published