ABSTRACT We present the analysis of spatially resolved spectroscopic observations of the born-again planetary nebula (PN) A 78 that are used to investigate the chemistry and physical properties of its three main morphological components, namely the inner knots, its eye-like structure, and the low surface-brightness outer nebula. The H-poor chemical abundances of the inner knots confirm the born-again nature of A 78, with an N/O abundances ratio consistent with the predictions of very late thermal pulses (VLTP). On the other hand, the high Ne/O is not expected in VLTP events, which prompts a possible different evolutionary path may be involving a binary system. The low N/O ratio and He/H abundances of the outer shell are indicative of a low-mass progenitor, whereas the chemical abundances of the eye-like structure, which results from the interaction between the H-poor born-again material and the outer nebula, evidence their mixture. Unlike previous works, the extinction is found to be inhomogeneous, being much higher towards the H-poor inner knots, where the presence of large amounts of C-rich dust has been previously reported. Dust-rich material seems to diffuse into outer nebular regions, resulting in zones of enhanced extinction.