Published in
American Society for Microbiology, Journal of Clinical Microbiology, 8(59), 2021
DOI: 10.1128/jcm.00238-21
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Occurrence of the p019 Gene in the bla <sub>KPC</sub> -Harboring Plasmids: Adverse Clinical Impact for Direct Tracking of KPC-Producing Klebsiella pneumoniae by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
Journal article published in 2021 by
Eva Gato,
Ignacio Pedro Constanso,
Bruno Kotska Rodiño-Janeiro,
Paula Guijarro-Sánchez 
,
Tyler Alioto,
Manuel Jesús Arroyo,
Gema Méndez,
Luis Mancera,
Marta Gut,
Ivo Gut,
Miguel Álvarez-Tejado,
Germán Bou,
Marina Oviaño
,
Tyler Alioto,
Manuel Jesús Arroyo,
Gema Méndez,
Luis Mancera,
Marta Gut,
Ivo Gut,
Miguel Álvarez-Tejado,
Germán Bou,
Marina Oviaño
This paper is made freely available by the publisher.
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Abstract
Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) has recently been used for the direct detection of KPC-producing isolates by analysis of the 11,109 Da mass peak representing the P019 protein. In this study, we evaluate the presence of the 11,109 Da mass peak in a collection of 435 unduplicated Klebsiella pneumoniae clinical isolates.