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American Association for the Advancement of Science, Science Advances, 46(7), 2021

DOI: 10.1126/sciadv.abi8178

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A brain proteomic signature of incipient Alzheimer’s disease in young APOE ε4 carriers identifies novel drug targets

Journal article published in 2021 by Jackson A. Roberts ORCID, Vijay R. Varma, Yang An, Sudhir Varma ORCID, Julián Candia ORCID, Giovanna Fantoni, Vinod Tiwari ORCID, Carlos Anerillas ORCID, Andrew Williamson, Atsushi Saito, Tina Loeffler, Irene Schilcher, Ruin Moaddel ORCID, Mohammed Khadeer, Jacqueline Lovett and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Brain proteins altered in young APOE ε4 carriers are found decades later in Alzheimer’s disease and present novel drug targets.