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Taylor and Francis Group, RNA Biology, 6(8), p. 938-946, 2011

DOI: 10.4161/rna.8.6.16603

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Animal snoRNAs and scaRNAs with exceptional structures

Journal article published in 2011 by Manja Marz, Christian Höner zu Siederdissen, Andreas R. Gruber, Christian Höner zu Siederdissen, Christian Hoener Zu Siederdissen, Fabian Amman, Stefan Badelt, Sebastian Bartschat, Stephan H. Bernhart, Wolfgang Beyer, Stephanie Kehr, Ronny Lorenz ORCID, Andrea Tanzer ORCID, Dilmurat Yusuf, Hakim Tafer and other authors.
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The overwhelming majority of small nucleolar RNAs (snoRNAs) fall into two clearly defined classes characterized by distinctive secondary structures and sequence motifs. A small group of diverse ncRNAs, however, shares the hallmarks of one or both classes of snoRNAs but differs substantially from the norm in some respects. Here, we compile the available information on these exceptional cases, conduct a thorough homology search throughout the available metazoan genomes, provide improved and expanded alignments, and investigate the evolutionary histories of these ncRNA families as well as their mutual relationships.