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Rockefeller University Press, Journal of Cell Biology, 10(221), 2022

DOI: 10.1083/jcb.202208008

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Balancing cell polarity PARts through dephosphorylation

Journal article published in 2022 by André Barros-Carvalho, Eurico Morais-De-Sá ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

How cells spatially organize their plasma membrane, cytoskeleton, and cytoplasm remains a central question for cell biologists. In this issue of JCB, Calvi et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202201048) identify PP1 phosphatases as key regulators of C. elegans anterior–posterior polarity, by counterbalancing aPKC-mediated phosphorylation of PAR-2.