Abstract We present 127 new transit light curves for 39 hot Jupiter systems, obtained over the span of 5 yr by two ground-based telescopes. A homogeneous analysis of these newly collected light curves together with archived spectroscopic, photometric, and Doppler velocimetric data using EXOFASTv2 leads to a significant improvement in the physical and orbital parameters of each system. All of our stellar radii are constrained to accuracies of better than 3%. The planetary radii for 37 of our 39 targets are determined to accuracies of better than 5%. Compared to our results, the literature eccentricities are preferentially overestimated due to the Lucy–Sweeney bias. Our new photometric observations therefore allow for significant improvement in the orbital ephemerides of each system. Our correction of the future transit window amounts to a change exceeding 10 minutes for 10 targets at the time of James Webb Space Telescope's launch, including a 72 minutes change for WASP-56. The measured transit midtimes for both literature light curves and our new photometry show no significant deviations from the updated linear ephemerides, ruling out in each system the presence of companion planets with masses greater than 0.39–5.0 M _⊕, 1.23–14.36 M _⊕, 1.65–21.18 M _⊕, and 0.69–6.75 M _⊕ near the 1:2, 2:3, 3:2, and 2:1 resonances with the hot Jupiters, respectively, at a confidence level of ±1σ. The absence of resonant companion planets in the hot Jupiter systems is inconsistent with the conventional expectation from disk migration.