ABSTRACT We present our second catalogue of quadruple star candidates, containing 101 systems discovered in TESS Full-Frame Image data. The targets were initially detected as eclipsing binary stars with the help of supervised machine learning methods applied to sectors (Sectors 1 through 54). A dedicated team of citizen scientists subsequently identified through visual inspection two sets of eclipses following two different periods. All 101 systems presented here pass comprehensive photocenter motion tests confirming that both sets of eclipses originate from the target star. Some of the systems exhibit prominent eclipse time variations suggesting dynamical interactions between the two component binary stars. One target is an eclipsing quintuple candidate with a (2 + 1) + 2 hierarchical configuration, such that the (2 + 1) subsystem produces eclipses on the triple orbit as well. Another has recently been confirmed as the second shortest period quadruple reported to date. This catalogue provides ephemerides, eclipse depths and durations, sample statistics, and highlights potentially interesting targets for future studies.