Abstract Purpose of Review Forests provide multiple ecosystem services (ES) to society, and the demand for ES is growing at the global level. However, how to manage forests for the provision of multiple and sometimes conflicting services is a complex and still unresolved issue. In this study, we reviewed the scientific literature for the period 2010–2020 dealing with forest management and multiple ES in Mediterranean forests, with the aim of (1) outlining the progress in research, (2) identifying knowledge gaps and research needs, and (3) discussing management approaches considering multiple ES. The selected literature was analyzed considering different aspects of multiple ES (e.g., drivers of changes, modeling approaches, trade-offs, and synergies). Recent Findings Our results show that wood production is still one of the main management objectives, with an increasing attention toward non wood forest products. Carbon sequestration and biodiversity were the most investigated regulating functions, but also specific aspects are gaining attention (e.g., lichens for microclimate regulation). Changes in stand structure and density, the impact of coppice vs. high forest, and the effect of management practices vs. abandonment were considered as drivers of change at the stand/management unit scale, while the impact of climate changes and disturbances were considered at the landscape/regional scale using modeling. Summary Despite the progress made in the last decade, our review highlights that further research is needed to fill the gaps in the scientific literature regarding how forest management influences the provision of multiple ES in the Mediterranean region. From a conceptual point of view, there is the need for a shift to a new paradigm based on an adaptable, flexible management, and planning approach to sustain self-organization, adaptive capacity, and overall resilience of Mediterranean forests, overcoming the ecosystem “service” approach; operatively, research should move toward a transdisciplinary approach, which considers problems from a diversity of points of view and involves extended peer communities not only in the dissemination of research results, but also in the research process itself.