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Royal Society of Chemistry, Chemical Science, 30(13), p. 8813-8820, 2022

DOI: 10.1039/d2sc02021a

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A pH-independent electrochemical aptamer-based biosensor supports quantitative, real-time measurement in vivo

Journal article published in 2022 by Shaoguang Li ORCID, Andrés Ferrer-Ruiz ORCID, Jun Dai ORCID, Javier Ramos-Soriano ORCID, Xuewei Du ORCID, Man Zhu ORCID, Wanxue Zhang ORCID, Yuanyuan Wang ORCID, M. Ángeles Herranz ORCID, Le Jing ORCID, Zishuo Zhang ORCID, Hui Li ORCID, Fan Xia ORCID, Nazario Martín ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

An electrochemical aptamer-based sensor, enabling in vivo measurements of drug concentrations directly in the bladder of living rats under pH-variable conditions, was developed employing a π-extended tetrathiafulvalene (exTTF) as redox reported.