Published in
American Society for Microbiology, Journal of Clinical Microbiology, 1(60), 2022
DOI: 10.1128/jcm.01698-21
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External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European Laboratories
,
Tim Roloff,
Michael Huber,
Samuel Cordey,
Alban Ramette ,
Yannick Gerth,
Claire Bertelli ,
Madlen Stange,
Helena M. B. Seth-Smith ,
Alfredo Mari ,
Karoline Leuzinger,
Lorenzo Cerutti,
Keith Harshman,
Ioannis Xenarios,
Philippe Le Mercier
and other authors.
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Abstract
This first pilot trial on external quality assessment (EQA) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) whole-genome sequencing, initiated by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Genomic and Molecular Diagnostics (ESGMD) and the Swiss Society for Microbiology (SSM), aims to build a framework between laboratories in order to improve pathogen surveillance sequencing. Ten samples with various viral loads were sent out to 15 clinical laboratories that had free choice of sequencing methods and bioinformatic analyses.