Published in
American Society for Microbiology, Microbiology Spectrum, 1(10), 2022
DOI: 10.1128/spectrum.01271-21
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Lipid and nucleocapsid N-protein accumulation in COVID-19 patient lung and infected cells
Journal article published in 2021 by
Anita E. Grootemaat,
Sanne van der Niet,
Edwin R. Scholl 
,
Eva Roos,
Bernadette Schurink,
Marianna Bugiani,
Sara E. Miller,
Per Larsen,
Jeannette Pankras,
Eric A. Reits,
Nicole N. van der Wel
,
Eva Roos,
Bernadette Schurink,
Marianna Bugiani,
Sara E. Miller,
Per Larsen,
Jeannette Pankras,
Eric A. Reits,
Nicole N. van der Wel
This paper is made freely available by the publisher.
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Abstract
Visualization of the subcellular localization of SARS-CoV-2 proteins in lung patient material of COVID-19 patients is important for the understanding of this new virus. We detected viral proteins in the context of the ultrastructure of infected cells and tissues and discovered that some viral proteins accumulate in novel, lipid-filled compartments.