Published in
American Society for Microbiology, Microbiology Spectrum, 6(10), 2022
DOI: 10.1128/spectrum.02305-22
Links
Tools
Using a 29-mRNA Host Response Classifier To Detect Bacterial Coinfections and Predict Outcomes in COVID-19 Patients Presenting to the Emergency Department.
Journal article published in 2022 by
Lauren de la Parte,
Nikhil Ram-Mohan,
Angela J. Rogers 
,
Catherine A. Blish ,
Marjan M. Hashemi,
Kristel C. Tjandra,
Jennifer A. Newberry,
Kari C. Nadeau,
Andra L. Blomkalns,
Ruth O’Hara,
Euan Ashley,
Rosen Mann,
Elizabeth J. Zudock,
Anita Visweswaran,
Thanmayi Ranganath
and other authors.
,
Catherine A. Blish ,
Marjan M. Hashemi,
Kristel C. Tjandra,
Jennifer A. Newberry,
Kari C. Nadeau,
Andra L. Blomkalns,
Ruth O’Hara,
Euan Ashley,
Rosen Mann,
Elizabeth J. Zudock,
Anita Visweswaran,
Thanmayi Ranganath
and other authors.
This paper is made freely available by the publisher.
Full text: Download
Data provided by 
Abstract
We assay the utility of the single-test IMX-BVN-3/IMX-SEV-3 classifiers that require just 2.5 mL of patient blood in concurrently detecting viral and bacterial infections as well as predicting the severity and 30-day outcome from the infection. A point-of-care device, in development, will circumvent the need for blood culturing and drastically reduce the time needed to detect an infection.