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European Centre for Disease Prevention and Control, Eurosurveillance, 6(27), 2022

DOI: 10.2807/1560-7917.es.2022.27.6.2200042

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Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021

Journal article published in 2022 by Jantien A. Backer ORCID, Dirk Eggink ORCID, Stijn P. Andeweg ORCID, Irene K. Veldhuijzen ORCID, Noortje van Maarseveen, Klaas Vermaas ORCID, Boris Vlaemynck, Raf Schepers, Susan van den Hof ORCID, Chantal Bem Reusken ORCID, Jacco Wallinga ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The SARS-CoV-2 Omicron variant has a growth advantage over the Delta variant because of higher transmissibility, immune evasion or shorter serial interval. Using S gene target failure (SGTF) as indication for Omicron BA.1, we identified 908 SGTF and 1,621 non-SGTF serial intervals in the same period. Within households, the mean serial interval for SGTF cases was 0.2–0.6 days shorter than for non-SGTF cases. This suggests that the growth advantage of Omicron is partly due to a shorter serial interval.