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American Association for the Advancement of Science, Science Advances, 32(7), 2021

DOI: 10.1126/sciadv.abh2944

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Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants

Journal article published in 2021 by Helena de Puig ORCID, Rose A. Lee, Devora Najjar ORCID, Xiao Tan, Luis R. Soenksen ORCID, Nicolaas M. Angenent-Mari ORCID, Nina M. Donghia ORCID, Nicole E. Weckman, Audrey Ory, Carlos F. Ng, Peter Q. Nguyen ORCID, Angelo S. Mao ORCID, Thomas C. Ferrante, Geoffrey Lansberry ORCID, Hani Sallum and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

An integrated, low-cost, sample-to-answer, CRISPR-based diagnostic detects SARS-CoV-2 and variants from unprocessed saliva.