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American Association for the Advancement of Science, Science Immunology, 62(6), 2021

DOI: 10.1126/sciimmunol.abl4340

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Autoantibodies neutralizing type I IFNs are present in <b>~</b>4% of uninfected individuals over 70 years old and account for <b>~</b>20% of COVID-19 deaths.

Journal article published in 2021 by Şadiye Kübra Tüter Öz, Esra Akyüz Özkan, Antonio Íñigo-Campos, Tayfun Özçelik, Tom van der Poll, Marc van der Valk, Horst von Bernuth, Maria Yolanda Ruiz del Prado, Etablissement du Sang study group, Aliénor de la Chapelle, Martín Castillo de Vera, Eric d’Ortenzio, Michiel van Agtmael, Frank van Baarle, Niels van Mourik and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Autoantibodies neutralizing type I IFNs increase in prevalence over 60 years of age and underlie about 20% of all fatal COVID-19 cases.