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Cambridge University Press, Epidemiology and Infection, (149), 2021

DOI: 10.1017/s0950268821001928

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SARS-CoV-2 immunogenicity in individuals infected before and after COVID-19 vaccination: Israel, January–March 2021

Journal article published in 2021 by Kamal Abu Jabal ORCID, Hila Ben-Amram, Karine Beiruti, Ira Brimat, Ashraf Abu Saada, Younes Bathish, Christian Sussan, Salman Zarka, Michael Edelstein ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Abstract Between December 2020 and March 2021, we measured anti-SARS-CoV-2 IgG titres among 725 Israeli hospital workers vaccinated against COVID-19. Infection post-dose 1 vaccination did not increase IgG titres, and individuals infected post-dose 1 had IgG levels comparable to never-infected individuals who received a single dose, lower than fully vaccinated, never-infected individuals. This suggests dose 2, currently not offered to those infected post-dose 1, may be required in these individuals. Larger studies should confirm whether individuals infected post-dose 1 need the second.