AbstractRecent numerical models of the multiphase ISM underline the importance of cosmic rays and magnetic fields for the physics of the ISM in disc galaxies. Observations of properties of the ISM in galactic halos constrain models of the expected exchange of matter between the star-forming disc and the environment (circumgalactic medium, CGM). We present new observational evidence from radio-continuum polarization studies of edge-on galaxies on magnetic field strength and structure as well as cosmic ray electron transport in galactic halos. The findings are discussed in the context of the disk-halo interaction of the interstellar medium. In addition, it is also briefly demonstrated how recent LOFAR observations of edge-on galaxies further constrain the extent of magnetic fields in galactic halos.