Through the advancement of non-invasive neuroimaging techniques, functional brain imaging research has gained widespread acceptance and increased clinical applications. In Taiwan, similar advances are also emerging, particularly in the integration of multi-modal neuroimaging. However, due to the relative limited local resources and infrastructure desirable for such an endeavor to flourish, we have ventured into collaborating with neighboring countries within the Pacific Rim region such as Japan and the Philippines) using grid technology. This perspectives paper highlights transdisciplinary collaborative efforts within Taiwan, as well as its' neighboring countries within the Pacific Rim. We first present a domestic example of ongoing collaborative efforts in integrating imaging techniques, such as functional magnetic resonance imaging (fMRI), diffusion spectrum imaging (DSI), and transcranial magnetic stimulation (TMS) to understand targeted neurocircuitries that may be compromised by psychiatric or neurological diseases, for the purpose of developing plausible treatment strategies. Second, we illustrate how such an international collaboration, with a common mission of translating neuroimaging techniques into clinical applications, could benefit strategic interests for all parties involved. Finally, we briefly discuss the constraints and challenges involved with developing such collaborative efforts amongst the Pacific Rim countries, and the possible impact it may have in healthcare provision for the region. ; 光電生物醫學研究中心 ; 醫學院 ; 期刊論文