Published in
American Physiological Society, American Journal of Physiology - Heart and Circulatory Physiology, 2(320), p. H838-H853, 2021
DOI: 10.1152/ajpheart.00736.2019
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New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans
Journal article published in 2021 by
Laura Ferté,
Alice Marino,
Sylvain Battault,
Laurent Bultot 
,
Anne Van Steenbergen,
Anne Bol,
Julien Cumps,
Audrey Ginion,
Hermann Koepsell ,
Laure Dumoutier,
Louis Hue,
Sandrine Horman,
Luc Bertrand ,
Christophe Beauloye
,
Anne Van Steenbergen,
Anne Bol,
Julien Cumps,
Audrey Ginion,
Hermann Koepsell ,
Laure Dumoutier,
Louis Hue,
Sandrine Horman,
Luc Bertrand ,
Christophe Beauloye
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Abstract
Ever since the discovery of its expression in the heart, SGLT1 has been considered as similar as the intestine and a potential contributor to cardiac glucose transport. For the first time, we have demonstrated that a slc5a1 transcript variant is present in the heart that has no significant impact on cardiac glucose handling.