In earlier chapters, we described the many advances in our understanding of schizophrenia. Unfortunately, we still do not have a detailed blueprint of what exactly goes wrong in the brain in schizophrenia, or a means for ‘fixing’ the brain. But even without a clear grasp of all the underlying, hidden facts, we have still made many gains. While we search for more clues, we need to use the facts on hand to help individuals with schizophrenia and their families to relieve their suffering. As the saying goes, ‘The perfect is the enemy of the good’, and some good treatment options exist. So while we work toward a perfect under­standing of schizophrenia and develop treatments that are targeted toward each individual’s personal form of the disorder, we must rely on the evidence for existing treatments to separate the ‘good’ from the ‘bad’. Bad treatments are those that are ineffective, counterproductive, or have a high risk of very serious side effects. Good treatments are those that have good evidence of helping a fair number of patients to reduce at least the positive symptoms of the disorder while having a relatively low risk of serious side effects. No current treatment for the disorder will work for all affected individuals, and we do not yet have a way of being able to tell before treatment what chance the affected individual has of improving with a given treatment. These are all goals for future research, including the discovery of brand new medicines. For now, we review the cur­rently available treatments with the best evidence of being able to help a good number of patients. The onset of schizophrenia can be frightening, for both affected individuals and their families. Affected individuals begin to express many odd beliefs: that people are trying to harm them— friends, relatives, strangers, or celebrities; that others can hear their thoughts as if spoken aloud; that voices talk to them, even when they are alone. In addition, they cannot express feelings and thoughts clearly and are frustrated by the doubts expressed by relatives and friends.