Published in
American Association for the Advancement of Science, Science Advances, 43(6), 2020
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The structural basis for Z α1-antitrypsin polymerization in the liver
Journal article published in 2020 by
Sarah V. Faull 
,
Emma L. K. Elliston ,
Bibek Gooptu ,
Alistair M. Jagger ,
Ibrahim Aldobiyan,
Adam Redzej ,
Magd Badaoui ,
Nina Heyer-Chauhan ,
S. Tamir Rashid ,
Gary M. Reynolds ,
David H. Adams ,
Elena Miranda,
Elena V. Orlova ,
James A. Irving ,
David A. Lomas
,
Emma L. K. Elliston ,
Bibek Gooptu ,
Alistair M. Jagger ,
Ibrahim Aldobiyan,
Adam Redzej ,
Magd Badaoui ,
Nina Heyer-Chauhan ,
S. Tamir Rashid ,
Gary M. Reynolds ,
David H. Adams ,
Elena Miranda,
Elena V. Orlova ,
James A. Irving ,
David A. Lomas
This paper is made freely available by the publisher.
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Abstract
α 1 -Antitrypsin polymers from human tissue have a structure most consistent with an intermolecular C-terminal domain swap.