A brief technical and economic insight into producing the water-soluble yellow colorant limocitrol 3-O-6″-[3-hydroxyl-3-methylglutaryl)])-β-d-glucopyranoside from waste lemon peel via simple solid–liquid extraction in aqueous ethanol or via hydrodynamic cavitation of waste lemon peel in water shows that the biocolorant can be obtained with multiple technical and economic advantages. Coupled with the simplicity and sustainability of the extraction processes suggested, the high chemical and physical stability of this polymethoxylated flavonol and the health benefits of citrus flavonoids support industrialization of this new bioeconomy production.