Published in
Lippincott, Williams & Wilkins, Transplantation, 1(92), p. 41-47, 2011
DOI: 10.1097/tp.0b013e31821cdf0d
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Pretransplant IgG subclasses of donor-specific human leukocyte antigen antibodies and development of antibody-mediated rejection
Journal article published in 2011 by
Gideon Hönger,
Helmut Hopfer,
Marie-Luise Arnold,
Bernd M. Spriewald,
Stefan Schaub,
Patrizia Amico
This paper is made freely available by the publisher.
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Abstract
The subclass of IgG antibodies contributes to their capability to activate complement. It is currently unknown whether the pretransplant IgG subclass composition allows distinguishing harmful from presumably irrelevant donor-specific human leukocyte antigen (HLA) antibodies (HLA-DSA) detected by single-antigen flow beads (SAFB).