Abstract In this paper, taking Nanjing Mochou Lake Metro Station as an example, the key technologies for the construction of super-deep stations near existing lines in the flood land area of the Yangtze River are studied. Mochou Lake Station is located in Mochou Lake Park on the Qinhuai River. It is a four-level underground island-type platform station, which is interchanged with the existing Line 2 Mochou Lake Station. The station used the “two-light and two-dark” construction method. The first and the second underground floor of the station used an open excavation order method, and the third and the fourth underground floor used to cover and cut-bottom up method. According to the monitoring results and settlement analysis results of the main structure, the construction method of “two-, light and two-dark, ” can help control the deformation of the construction area and ensure the safety of the surrounding structures and existing stations.