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American Association for the Advancement of Science, Science Advances, 14(6), 2020

DOI: 10.1126/sciadv.aax5692

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Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Stem cell identity is maintained by diverse Polycomb complexes cooperating to ensure robust silencing of key developmental genes.