Published in
American Association for the Advancement of Science, Science Translational Medicine, 503(11), 2019
DOI: 10.1126/scitranslmed.aaw4993
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The androgen receptor regulates a druggable translational regulon in advanced prostate cancer
Journal article published in 2019 by
Yuzhen Liu 
,
Lexiaochuan Wen,
Yu C. Yang ,
Robin G. Tharakan,
Takuma Uo,
Smitha P. S. Pillai,
Colm Morrissey ,
Stephen R. Plymate,
Peter S. Nelson,
Jessie L. Horn ,
Kalyan Banda ,
Asha Z. Goodman,
Yiting Lim,
Sujata Jana ,
Sonali Arora
and other authors.
,
Lexiaochuan Wen,
Yu C. Yang ,
Robin G. Tharakan,
Takuma Uo,
Smitha P. S. Pillai,
Colm Morrissey ,
Stephen R. Plymate,
Peter S. Nelson,
Jessie L. Horn ,
Kalyan Banda ,
Asha Z. Goodman,
Yiting Lim,
Sujata Jana ,
Sonali Arora
and other authors.
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Abstract
The androgen receptor (AR) regulates mRNA-specific translation through 4EBP1, which is a druggable vulnerability in AR-deficient prostate cancer.