Intelligent transportation solutions and smart information and communication technologies will be the core of future smart cities. For this purpose, these topics have captivated noteworthy interest in the investigation and construction of cleverer communication protocols or the application of artificial intelligence in the connection of in-vehicle devices by wireless networks, and in in-vehicle services for autonomous driving using high-precision positioning and sensing systems. This special issue has focused on the collection of high-quality papers aimed at solving open technical problems and challenges typical of mobile communications for Intelligent Transportation Systems.