Published in
Springer, Diabetologia, 8(55), p. 2193-2204, 2012
DOI: 10.1007/s00125-012-2560-y
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Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis.
Journal article published in 2012 by
M. Islam,
Th H. Jafar,
Ar R. Wood,
Nm M. G. De Silva,
M. Caulfield,
N. Chaturvedi,
Tm M. Frayling 
This paper is made freely available by the publisher.
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Abstract
Multiple genetic variants are associated with type 2 diabetes-related traits in Europeans, but their role in South Asian populations needs further study. We hypothesised that genetic variants associated with diabetes-related traits in Europeans would explain a similar proportion of phenotypic variance in a Pakistani population and could be used in Mendelian randomisation analyses.