Published in

American Association for the Advancement of Science, Science, 6188(344), p. 1168-1173, 2014

DOI: 10.1126/science.1252806

Links

Tools

Export citation

Search in Google Scholar

The Sheep Genome Illuminates Biology of the Rumen and Lipid Metabolism

Journal article published in 2014 by Yu Jiang, Min Xie, Wenbin Chen, Searle Smj, Richard Talbot, Jillian F. Maddox, Barris Wc, Cam Gr, Thomas Faraut, Aken Bl, Chunhua Wu, Donna M. Muzny, Stanton Ja, Yuxiang Li, Wenguang Zhang and other authors.
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Sheep (Ovis aries) are a major source of meat, milk, and fiber in the form of wool and represent a distinct class of animals that have a specialized digestive organ, the rumen, that carries out the initial digestion of plant material. We have developed and analyzed a high-quality reference sheep genome and transcriptomes from 40 different tissues. We identified highly expressed genes encoding keratin cross-linking proteins associated with rumen evolution. We also identified genes involved in lipid metabolism that had been amplified and/or had altered tissue expression patterns. This may be in response to changes in the barrier lipids of the skin, an interaction between lipid metabolism and wool synthesis, and an increased role of volatile fatty acids in ruminants compared with nonruminant animals. ; Yu Jiang . David L. Adelson . et al.