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Oxford University Press, Nucleic Acids Research, D1(41), p. D579-D583, 2012

DOI: 10.1093/nar/gks1220

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ViralZone: recent updates to the virus knowledge resource

Journal article published in 2012 by Patrick Masson, Chantal Hulo, Edouard De Castro, Hans Bitter, Lore Gruenbaum, Laurent Essioux, Lydie Bougueleret, Ioannis Xenarios ORCID, Philippe Le Mercier, Philippe Le Mercier
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ViralZone (http://viralzone.expasy.org) is a knowledge repository that allows users to learn about viruses including their virion structure, replication cycle and host–virus interactions. The information is divided into viral fact sheets that describe virion shape, molecular biology and epidemiology for each viral genus, with links to the corresponding annotated proteomes of UniProtKB. Each viral genus page contains detailed illustrations, text and PubMed references. This new update provides a linked view of viral molecular biology through 133 new viral ontology pages that describe common steps of viral replication cycles shared by several viral genera. This viral cell-cycle ontology is also represented in UniProtKB in the form of annotated keywords. In this way, users can navigate from the description of a replication-cycle event, to the viral genus concerned, and the associated UniProtKB protein records.