The Royal Society, Philosophical Transactions of the Royal Society B: Biological Sciences, 1584(366), p. 3635-3637, 2011
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Cell biologists are interested in how complexity arises from the interaction of different molecules. However, cells are many orders of magnitude larger than the protein-binding interfaces. To bridge these vast difference in scales, biologists construct hierarchies of organization of cellular structures. I describe how systems biology provides an approach to bridge these different scales.