Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 10(62), 2018
DOI: 10.1128/aac.01306-18
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Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam
Journal article published in 2018 by
Fekade B. Sime,
Saurabh Pandey,
Nermin Karamujic,
Suzanne Parker,
Elizabeth Alexander,
Jeffery Loutit,
Stephanie Durso,
David Griffith,
Jeffrey Lipman,
Steven C. Wallis,
Jason A. Roberts 
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
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Abstract
The combination product meropenem-vaborbactam, with activity against KPC-producing carbapenem-resistant Enterobacteriaceae , is likely to be used during renal replacement therapy. The aim of this work was to describe the extracorporeal removal (adsorption and clearance) of meropenem-vaborbactam during continuous venovenous hemofiltration (CVVH).