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Springer Verlag, European Journal of Applied Physiology, 2(106), p. 217-227

DOI: 10.1007/s00421-009-1009-6

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WISE-2005: effect of aerobic and resistive exercises on orthostatic tolerance during 60 days bed rest in women

Journal article published in 2009 by Patrick Guinet, Suzanne M. Schneider, Brandon R. Macias, Donald E. Watenpaugh, Richard L. Hughson ORCID, Anne Pavy Le Traon, Anne Pavy Le Traon, Jean-Yves Bansard, Alan R. Hargens
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Cardiovascular deconditioning after long duration spaceflight is especially challenging in women who have a lower orthostatic tolerance (OT) compared with men. We hypothesized that an exercise prescription, combining supine aerobic treadmill exercise in a lower body negative pressure (LBNP) chamber followed by 10 min of resting LBNP, three to four times a week, and flywheel resistive training every third day would maintain orthostatic tolerance (OT) in women during a 60-day head-down-tilt bed rest (HDBR). Sixteen women were assigned to two groups (exercise, control). Pre and post HDBR OT was assessed with a tilt/LBNP test until presyncope. OT time (mean +/- SE) decreased from 17.5 +/- 1.0 min to 9.1 +/- 1.5 min (-50 +/- 6%) in control group (P